DS13 A comparative study between recipient site preparation using manual dermabrasion and tattooing pen in autologous noncultured epidermal cell suspension procedure in stable vitiligo patients: a randomized double blinded study

Abstract Vitiligo is a common acquired disorder of depigmentation that occurs as result melanocyte loss. Surgical therapies are indicated in patients with stable disease who fail to respond medical therapies. This mostly includes autologous grafting techniques both tissue and cellular (both cultured noncultured). Common recipient site preparation include dermabrasion, suction blistering, liquid nitrogen, electrofulguration microneedling. The aim was assess the difference extent repigmentation manual dermabrasion tattooing pen noncultured epidermal cell suspension on vitiligo patches. prospective intraindividual comparative study. Thirty-six were recruited. Patients had clinical diagnosis segmental or nonsegmental two independent patches 3 × cm more present either symmetrically unilaterally over same body single patch 6 more. lesions been for ≥ 1 year. At week 24, proportion achieving > 75% 86%. In contrast, 61% group achieved repigmentation. 50% 89% vs. 72% group. Eighty per cent at acral sites 94% nonacral patches, whereas group, 47% 73.3% terms colour matching, 24 weeks, good matching surrounding normal skin obtained 80% groups. There significant efficacy between methods favour dermabrasion. Tattooing delivery has advantage it less time consuming also reduces Recipient by showed higher rate infection 4 weeks (25% 6%). halo phenomena comparable groups, no seen. Patient satisfaction physician global assessment score Quality Life index (VitiQoL) methods,